Both Oxitec and independent collaborators around the world have conducted extensive testing on Oxitec’s OX513A mosquitoes. Oxitec insects have been tested by laboratories including the Institute Pasteur in Paris, the Gorgas Institute in Panama, the Institute for Medical Research in Malaysia, University of Colorado, USA and UHUHS, USA. The Centre for Medical and Veterinary Entomology at Gainesville have also tested our mosquitoes in outdoor cage trials. The USDA APHIS CPHST has tested the same approach in other insect species and a thorough examination of the risks and benefits has been conducted under the National Environmental Protection Act (NEPA), which concluded that the use of this technology was ‘environmentally preferable’ to alternatives.
For outdoor trials, these have been carried out by the Mosquito Research and Control Unit Cayman, the Gorgas Institute in Panama, the Institute for Medical Research in Malaysia, Moscamed and the University of Sao Paulo in Brazil.
These studies have shown that our technology can reduce a field population of Aedes aegypti by over 90%.
Oxitec uses (accredited) third-party labs where appropriate to carry out studies to produce data for regulatory submissions including testing of non-target organisms such as fish that could eat mosquitos, determining environmental concentrations of tetracyclines and analysis of the genes for toxicity and allergenicity.
Harris, A. F., Nimmo, D., McKemey, A. R., Kelly, N., Scaife, S., Beech, C., Petrie, W., and Alphey, L. (2011) Field performance of engineered male mosquitoes. Nature Biotechnology