Publications

McKemey, A., Alphey, L., Koukidou, M., Kramer, A. (2010) Genetic Improvements to SIT for Fruit Fly Control(2010) RIDL SIT Olivefly IOBC.  Integrated Protection of Olive Crops 53: 11- 16

Fu, G., Lees, R.S., Nimmo, D., Aw, D., Jin, L., Gray, P., Berendonk, T.U., White-Cooper, H., Scaife, S., Phuc, H.K., Marinotti, O., Jasinskiene, N., James, A.A. and Alphey, L. A female-specific flightless phenotype for mosquito control. PNAS, submitted

Alphey, L., Benedict, M.Q., Bellini, R., Clark, G.G., Dame, D.A., Service, M.W. and Dobson, S.L. (2009) Sterile-insect methods for control of mosquito-borne diseases – an analysis. Vector-Borne and Zoonotic Diseases, in press

Wilke, ABB., Nimmo, DD., St John, O., Kojin BB., Capurro, ML., Alphey, L. and Marrelli, MT. (2009) Transgenic mosquitoes to control vector populations. Asia Pacific Journal of Molecular Biology and Biotechnology 17 (3) in press

Beech, CJ., Vasan, SS, Quinlan, MM., Capurro, ML., Alphey, L., Bayard, V., Bouaré, M., Kittayapong, P., Lavery, J.V. Lim, LH., Marrelli, MT., McLeod, MC., Nagaraju, J., Ombongi, K., Othman, RY., Pillai, V., Ramsey, JM., Reuben, R., Rose, RL., Tyagi, B.K. and Mumford, J. (2009) Deployment of innovative genetic vector control strategies: Progress on regulatory and biosafety aspects, capacity building and development of best-practice guidance. Asia Pacific Journal of Molecular Biology and Biotechnology 17 (3) in press

Mumford, J., Quinlan, MM., Beech, C., Alphey, L., Bayard, V., Capurro, ML., Kittayapong, P., Knight, JD., Marrelli, MT., Ombongi, K., Ramsey, JM. and Reuben, R. (2009) MosqGuide: A project to develop best practice guidance for the deployment of innovative genetic vector control strategies for malaria and dengue. Asia Pacific Journal of Molecular Biology and Biotechnology 17 (3) in press

Morrison, N., Segura, D.F., Stainton, K.C., Fu, G., Donnelly, C.A and Alphey, L. (2009) Sexual competitiveness of a transgenic sexing strain of the Mediterranean fruit fly, Ceratitis capitata. Entomologia Experimentalis et Applicata 133: 146-153

Alphey, L. (2009) Natural and engineered mosquito immunity. Journal of Biology 8: 40

Papathanos, P.A., Bossin, H.C., Benedict, M.Q., Catteruccia, F., Malcolm, C.A., Alphey, L. and Crisanti, A. (2009) Sex separation strategies: past experience and new approaches. Malaria Journal 8 (Suppl 2): S5

Alphey, N, Bonsall, M.B., Alphey, L. (2009) Combining pest control and resistance management: synergy of engineered insects with Bt crops. Journal of Economic Entomology, 102: 717-732

Condon, K.C., Condon, G.C., Dafa’alla, T.H., Forrester, O.T., Phillips, C.E., Scaife, S. and Alphey, L. (2007). Germ-line transformation of the Mexican Fruit Fly. Insect Molecular Biology, 16: 573-580.

Condon, K.C., Condon, G.C., Dafa’alla, T.H., Fu, G., Phillips, C.E., Jin, L., Gong, P. and Alphey, L. (2007). Genetic sexing through the use of Y-linked transgenes. Insect Biochemistry and Molecular Biology, 37: 1168-1176.

Guidance for Contained Field Trials of Vector Mosquitoes Engineered to Contain a Gene Drive System: Recommendations of a Scientific Working Group (2007). Vector-borne and Zoonotic Diseases, 8: 127-166

Alphey, N., Coleman, P.G., Donnelly, C.A. and Alphey, L. (2007). Managing insecticide resistance by mass release of engineered insects. Journal of Economic Entomology, 100: 1642-1649.

Simmons, G.S., Alphey, L., Vasquez, T., Morrison, N.I., Epton, M.J., Miller, E., Miller, T.A., Staten, R. (2007). Potential use of a conditional lethal transgenic pink bollworm Pectinophora gossypiella in area-wide eradication or suppression programmes. In M.J.B. Vreysen, A.S. Robinson and J. Hendrichs (eds.). Area-Wide Control of Insect Pests: From Research to Field Implementation, Springer, Dordrecht, The Netherlands.

Alphey, L. (2007). Engineering insects for the Sterile Insect Technique. In M.J.B. Vreysen, A.S. Robinson and J. Hendrichs (eds.). Area-Wide Control of Insect Pests: From Research to Field Implementation, Springer, Dordrecht, The Netherlands.

Phuc , H.K., Andreasen, M.H., Burton, R.S., Vass, C., Epton, M.J., Pape, G., Fu, G., Condon, K.C., Scaife, S., Donnelly, C.A., Coleman, P.G., White-Cooper, H. and Alphey, L. (2007) Late-acting dominant lethal genetic systems and mosquito control. BMC Biology. 5:11

Fu, G., Condon, K.C., Epton, M.J., Gong, P., Jin, L., Condon, G.C., Morrison, N.I., Dafa’alla, T. H. and Alphey, L. (2007) Female-specific insect lethality engineered using alternative splicing. Nature Biotech., 25:3

Atkinson, M.P., Su, Z., Alphey, N., Alphey, L.S., Coleman, P.G., Wein, L.M. (2007). Analyzing the control of mosquito-borne diseases y a dominant lethal genetic system. PNAS.104:22.

Dafa’alla, T.H., Condon, G.C., Condon, K.C., Phillips, C.E., Morrison, N.I., Jin, L., Epton, M.J., Fu, G. and Alphey, L. (2006). Transposon-free insertions for insect genetic engineering. Nature Biotech., 24: 820-821.

Marrelli, M.T., Moreira, C.K., Kelly, D., Alphey, L. and Jacobs-Lorena, M. (2006). Mosquito transgenesis: what is the fitness cost? Trends Parasit., u: 197-202.

Nimmo, D.D.,Alphey, L. Meredith, J.M. and Eggleston, P (2006). High efficiency site-specific genetic engineering of the mosquito genome. Insect Molecular Biology, 15: 129-136.

Olson, K.E., Alphey, L., Carlson, J. and James, A.A. (2006). Genetic approaches in Aedes aegypti for control of dengue: an overview. In “Bridging Laboratory and Field Research for Genetic Control of Disease Vectors”, eds Knols, B.G.J. and Louis, C. Springer ISBN: 1-4020-3800-3.

Gong, P., Epton, M.J., Fu, G., Scaife, S., Condon, K.C., Condon, G.C., Morrison, N.I., Dafa’alla, T., Coleman, P.G. and Alphey, L. (2005). A dominant lethal genetic system for autocidal control of the Mediterranean Fruit Fly. Nature Biotech., 23: 453-456.

Coleman, P.G. and Alphey, L. (2004). Genetic control of vector populations: an imminent prospect. Trop. Med. Int. Health, 9: 433-437.

Alphey, L., Beard, B., Billingsley, P., Coetzee, M., Crisanti, A., Curtis, C., Eggleston, P., Godfray, C., Hemingway, J., Jacobs-Lorena, M., James, AA., Kafatos, FC., Mukwaya, LG., Paton, M., Powell, JR., Schneider, W., Scott., TW., Sine, B., Sinden, R., Sinkins. S., Spielman, A., Touré, Y. and Collins, FH. (2002). Malaria control with genetically modified vectors. Science 298: 119-121.

Alphey, L. (2002). Re-engineering the Sterile Insect Technique. Insect Biochem. Mol. Biol., 32: 1243-1247.

Alphey, L. and Andreasen, M. (2002). Dominant lethality and insect population control. Mol. Biochem. Parasitology, 121: 173-178.

Bateson, P., Alphey, L., Bulfield, G., Fisher, E., Goodfellow, P., Keverne, B., McConnell, I., Owen, M., Raff, M., Smith, J., Cooper, R., Craig, J. and Teather, S. (2001). The use of GM animals. The Royal Society.

Alphey, L. (2000) Is RIDL the Answer? ISB News Report May 2000: 8-10.

Thomas, D.T., Donnelly, C.A., Wood, R.J. and Alphey, L.S. (2000). Insect population control using a dominant, repressible, lethal genetic system. Science, 287: 2474-2476.